At the CRCHUM, the development of patient-centred research is a priority for action. The knowledge generated by our research activity translates into direct benefits for citizens. Our research work provides a range of health care and intervention solutions for the entire population.


Major Pathology

Breasts, ovaries, prostate, lung

Health Care and Intervention Solutions
  • Personalized Medicine
  • Combination Therapies
  • Immunotherapy
  • Cell Therapy
Major Pathologies

Type 2 diabetes and its complications, hypertension, neural processes and nutrition

Health Care and Intervention Solutions
  • Precision Medicine
  • Precision Imaging
  • Prevention Programs
Major Pathologies

Transplantation, different types of Hepatitis, HIV, Autoimmune diseases, Osteoarthritis

Health Care and Intervention Solutions
  • Increase In Organs Donations
  • Vaccines
  • Precision Imaging
  • Immunotherapy
Major Pathologies

Multiple sclerosis, epilepsy, neurodegenerative diseases, stroke, addiction / mental health

Health Care and Intervention Solutions
  • Early Diagnosis
  • Immunotherapy
  • Improving The Care Trajectory


  • Virtual and augmented reality for analyzing and improving human movement or computer-assisted surgery
  • 3D printing for radiation oncology treatments
  • 3D tissue printing
  • Artificial intelligence
  • Center For The Integration and Analysis of Medical Data (CITADEL)

Giving Patient-Partners A Voice

The CRCHUM’s patient-partner committee, made up of patients and researchers, guides the CRCHUM’s management team as they introduce the patient-partner approach into their development priorities and research programs.

In the fall of 2018, this committee allowed two patient-partners to be appointed members of the CRCHUM’s scientific committee. It also established an awareness campaign for patients and citizens to promote the importance of research and the research cycle.

Key Contributions To The Quebec Life Sciences Strategy

To meet the standards of a world-class clinical research centre, in 2018 the CRCHUM established the Unit for Innovative Therapies (UIT) under the initiative of Dr. Rahima Jamal, a hemato-oncologist at the CHUM. The UIT allows patients whose treatment has failed to have access to new treatments and accelerate the development of such treatments. Developed in collaboration with several CRCHUM researchers, this project aims to strengthen the health care system, a priority established by the 2017-2027 Quebec Life Sciences Strategy. Major pharmaceutical companies are presently offering phase 1 clinical trials at the UIT. The unit also supports the CHUM’s innovative clinical research programs by facilitating the development of trials initiated by our researcher-investigators.

Centre de Recherche du Centre Hospitalier de l'Université de Montréal
The UIT Team; in the first row, in the usual order: Marie Martin, Catherine Péthel, Nathalie Éthier and Vanessa Hertig. Second row: Dre Rahima Jamal, Martine Comeau and Xavier Levac.

Precision medicine is another priority component of this Strategy, not only for the province, but for the health care system and the public as well. The CITADEL (Center for the Integration and Analysis of Medical Data), an integral part of the CHUM and its research centre, has been a repository for the medical and administrative data of some 4 million patients treated at the CHUM since 1998. Accessing and using this data has been a valuable asset for both researchers and managers, who can analyze medical conditions, health care and services and recommend improvements that will benefit patients. Consisting of computer engineers, data scientists and biostatisticians, the CITADEL team facilitates data processing and analysis for nearly 60 projects currently underway.

On the strength of this infrastructure unrivalled elsewhere in Quebec, the CRCHUM received $1.2M in funding from the Ministère de l’Économie et de l’Innovation to facilitate access to the clinical and administrative data of health institutions province-wide. This project involves Quebec’s largest institutions (CHUM, MUHC, CHU de Québec, CHU de Sherbrooke, MHI, Quebec Heart and Lung Institute, etc.).

Centre de Recherche du Centre Hospitalier de l'Université de Montréal
Dr. Michaël Chassé, scientific director of CITADEL

Global Visibility

A world-class research centre, the CRCHUM produces highquality knowledge output and mobilizes it widely across the scientific community, making it available to decision-makers and the public at large.

Here’s a summary of 2018-2019, a year filled with discoveries and awards that echo our practical objective of playing a leading role in improving health care and promoting health.



Rare brain disease in children: breakthrough in Rasmussen's encephalitis
- Dr. Alexandre Prat -


Shalini Lal appointed Canada Research Chair in Innovation and Technologies

Intestinal microbiota believed to influence response to anti-cancer immunotherapies
- Dr. Bertrand Routy -

Impact of the opioid crisis on the lives of people with chronic non-cancer pain in Quebec and British Columbia
- Manon Choinière -


Development of a unique cancer immunotherapy program at the CHUM
- Dr. Simon Turcotte -
- Dr. Rahima Jamal -
- Réjean Lapointe -

The CRCHUM and its partners form a consortium to fight cancer

Restoring communication between neurons to slow down glaucoma
- Adriana Di Polo -

Appointment of Vincent Dumez to Pharmacare's Advisory Council

Dr. Fred Saad inducted as a knight into Ordre national du Québec


A tool to identify adolescents at risk of smoking developed at the CRCHUM
- Marie-Pierre Sylvestre -
- Jennifer O'Loughlin -
- Nancy Hanusaik -

Interleukin IL-22, a new target to inhibit the progression of liver disease
- Naglaa Shoukry -

Career award given to Dr. Jean-Louis Chiasson by the Société Francophone du Diabète and Diabète Québec

Fight against HIV: patients with resistance provide a new molecular key
- Dr. Cécile Tremblay -


Editorial in the British Medical Journal by the Centre of Excellence on Partnership with Patients and the Public
- Dr. Antoine Boivin - and
Alexandre Grégoire, patient-partner



Claude Bernard Lyon 1 University (France) awards the title of Doctor honoris causa to Jacques A. de Guise

CRCHUM Awards of Excellence honouring health research
- Dr. Diane Provencher -

Young Researcher
- Dr. An Tang -

Scientific Contribution
- Adriana Di Polo -


Deep neural networks identify tumours
- Samuel Kadoury -
- Dr. An Tang -

The Paul-Lupien and Jean Davignon Founders' Award is given to Marc Prentki in recognition of his long-standing career

Nathalie Arbour appointed Claude-Bertrand Chair in neurosurgery at the Université de Montréal

Designing better embryos: breakthrough in the field of inferbility
- Greg FitzHarris -

Using anti-cancer immunotherapy to fight HIV
- Nicolas Chomont -
- Rémi Fromentin -


Dre Saima Hassan receives the Emerging Science Award for her commitment to fighting breast cancer (Fond de recherche Québec-Santé Career Award program)

Jean-Louis Denis inducted as a Fellow in the British Academy of Social Sciences

Developing Talents

Since its founding, the CRCHUM has actively supported the development of successful research teams. With its dynamic environment that allows research groups in emerging and translational niche sectors to thrive, the CRCHUM is able to attract new research leaders and recruit the best students. In 2018, 10 regular researchers joined the CRCHUM: Chantal Bémeur (Cardiometabolic theme); Marie-Claude Bourgeois-Daigneault, Gerardo Ferbeyre and Dr. Philip Wong (Cancer theme); Sophie Petropoulos and Sabrina Anh-Tu Hoa (Immunopathology theme); Dr. François-Martin Carrier, Emmanuelle Duceppe and Dr. Brian James Potter (Health Innovation and Evaluation Hub theme), Mark Keezer (Health Innovation and Evaluation Hub and Neuroscience themes).

A well-known training facility, the CRCHUM welcomes an average of nearly 650 students per year (undergraduate, masters, doctoral and postdoctoral trainees). Each of our researchers supervises on average three to five students, destined to become future research leaders.

In 2017, to facilitate recruiting the best students, the CRCHUM introduced an Open House Day where masters, doctoral and postdoctoral students could meet our research teams and discover the unique characteristics of a research environment in an ultraspecialized hospital setting. In the past three years, more than 200 students have taken part in this event. The 2019 event was once again a success.

Held annually, the Student Congress also provides young scientists with a platform for presenting their research results and meeting world-class researchers. The 20th conference saw a record number of participants and featured 140 abstracts and 110 posters. The Datablitz session, a concept introduced this year in which students had three minutes to present their research results, was also highly appreciated.

Centre de Recherche du Centre Hospitalier de l'Université de Montréal